Tadalafil 5mg Online: instruction
Tadalafil 5mg instruction
Tadalafil 5mg, intended for the treatment of erectile disfunction, is a crystalline substance, solid, practically insoluble in water. This is a selective inhibitor of the enzyme specific phosphodiesterase type 5, which in the smooth muscles of the cavernous body of the penis destroys the cyclic guanosine monophosphate, contributing to the expansion of vascular walls and the actual occurrence of erection. On the action of the funds were received only positive feedback, and side effects on the background of the effectiveness of the funds are called minor. The main component of the drug Tadalafil is a chemical with the same name and a small number of additional auxiliary components.
In a healthy man, with sexual arousal and / or sexual stimulation, there is a significant flow of blood through the arterial vessels of the penis, thereby providing an increase in pressure in the cavernous (cavernous) bodies. Due to the increase in the volume of the cavernous bodies, an obstruction of the venous blood outflow is created, after which an increase in the size and compaction of the penis occurs. With erectile disfunction, the normal blood supply process is accompanied by problems. The most common of these is the too rapid destruction of cGMP by the enzyme PDE-5, due to which the walls of the vessels relax, the density of the penis decreases and the erection decreases. Tadalafil 5mg can be shown with this problem, since its action is aimed at inhibiting PDE-5. Among the violations in which the drug can be an effective tool, psycho-emotional disorders, problems with hormones and metabolism.
According to its clinical action, the drug is a vasodilator (vasodilator). It has an inhibitory effect on the work of the PDE-5 enzyme, therefore, cGMP does not disintegrate for a long time, acts longer, which leads to the development of a stable erection. A prerequisite for the effective action of Tadalafil 5mg is the presence of natural sexual arousal and / or sexual stimulation. This is due to the fact that cGMP, necessary for the expansion of blood vessels, is produced under the influence of NO (nitric oxide), which in turn is released when excited. In the process of sexual arousal, the spinal cord and the brain exchange a number of impulses, a command is given to release nitric oxide, its action leads to the active production of cGMP and erection due to the expansion of the walls of blood vessels. Only then does Tadalafil, which strengthens and prolongs the action of the enzyme, makes the erection stable and long lasting. In other words, thanks to the drug, the natural process of arousal is enhanced and prolonged, but not artificially created.
Application Tadalafil 5mg
Studies have shown that the maximum effect is achieved when taking Tadalafil 5mg orally with a small amount of water, about a quarter of an hour before planned sexual intercourse. In the next 36 hours after taking the pill, attempts to commit a sexual act will be successful. The time to achieve the desired effect is calculated in each case individually, and it is important to remember that it is unacceptable to abuse the drug: the normal average dosage is no more than 20 mg when taken no more than once a day. The rate is that for men both middle-aged and elderly (over 65 years) age, dosage adjustment is not required. The use of the drug in combination with such drugs as Itraconazole, Ketoconazole, Nefazodone, Ritonavir, Saquinavir or Erythromycin, is allowed at a dosage of 10 mg no more than once every three days. Also with caution, Tadalafil 5mg is used when taking other drugs from the category of PDE-5 inhibitors. It is not allowed to combine the drug with analogues, also designed to combat manifestations of erectile disfunction. Marked rapid absorption of the drug and all components after administration.
Use of the drug is not strictly indicated for women and children under the age of 18 years. The drug is contraindicated in case of individual sensitivity, intolerance or allergy to the drug itself or its components, as well as when taking alpha-adrenergic blocking agents (Afluzosin, Ditamin, Prazosin, Tropafen, Phenoxybenzamine) and drugs, which include nitrates (Molstadomin, Nitroglycerin, Vt, Zyroxine, Zyroxylene, Vyroxine, Phenoksibenzamin) . Tadalafil 5mg should be used with caution in men with diagnosed diseases of the cardiovascular system, such as myocardial infarction, heart failure (higher class II), angina pectoris, arterial hypotension and cardiac arrhythmias, stroke. In hereditary degenerative diseases of the retina, severe liver failure, predisposition to the anatomical deformation of the penis and priapism, the drug can be taken only after consulting a specialist.
What to fear
The following side effects are possible with various manifestations when taking Tadalafil 5mg:
- headaches, dizziness
- problems with nasal congestion
- painful myalgic sensations
- eye pain, eyelid swelling with conjunctival redness
- dyspepsia symptoms
In case of overdose of the drug, a slight increase in side effects may occur, which is treated during standard maintenance therapy. Symptoms manifested in 5-15% of men taking the remedy. As practice shows, they develop during the first days after ingestion, they pass independently within 48 hours. Despite the fact that the described discomfort in some cases accompany an erection and to a certain extent worsen the impression of sexual intercourse, many men called side effects a permissible evil.